Toxic Chemical Update 9

 

Are Anti-psychotic drugs bad for Vietnam Veterans?

 

Below is just a partial issue for drugs taken for the symptoms of PTSD.  Including lawsuits using Veterans.

 

For the VA or anyone to come forward and now say they have this proposed magic pill probably worked on by those that developed Agent Orange and concluded how safe it was going to be used in untested quantities and untested formulas.

 

Like Doc Cahill I think this is, more in line with the government mandates not some magic pill.  The description of this new theory should start out as, Once upon a time in magic kingdom government; run and legislated by the Veterans Administration and the Department of Defense there was a magic cure discovered…

 

Veterans must realize this is a DOD/VA cost cutting effort, not a matter of science.  The government must stop the claims for PTSD otherwise; the DOD will have no budget left due to the cost of war. 

 

What I see in the future is a time limit put on 100% stress disability claims and only while the Veteran is seeking and participating in active VA treatment and reemployment studies as well as employment participation.  Very few if any 100% permanent disabilities will be granted.  I also see a time limit put on the manifestation of such disorders. 

 

Once this philosophy is in place then the omnipotent VA eventually will go after and probably are currently going after any 100% disability cases.  Even if they cut the 100% to 90%, 80% to 70%, and so forth; the savings will be in the hundreds of millions per year.

 

These conclusions are based on my participation at the VA disability commission in Silver Springs, MD and the questions and NAS/IOM studies that were being proposed and even some of the testimony of those there on the success of treating Veterans and getting them back into the work place and off of permanent disability. 

 

Of course, most of you know my stance with data on these issues with regard to our toxic chemical legacy and the Gulf War issues in these issues actually exacerbating any neuropsychological issues.  This is not some temporary condition that can be fixed with Anti-psychotic drugs.  Permanent biophysical on going damages are happening and have happened since the exposures.

 

Even though, for decades now the government has blamed many serious medical issues, caused by other government caused issues, on stress.  This includes the government-contracted agencies such as the NAS/IOM that found this stress caused all the disability, death, and offspring issues in a 100-hour war in Gulf War I.  Not very logical to say the least.

 


 

Injured by Seroquel?

 

Seroquel, the popular schizophrenia drug, manufactured by Astra Zeneca has been linked to a higher incidence of diabetes.  Data from a recent medical conference in Philadelphia showed patients on Seroquel had 3.34 times as many cases of diabetes as those on older drugs. 

The study was conducted on U.S. military veterans and demonstrated that Seroquel and other members of a new class of anti-psychotic drugs were linked to a higher risk of diabetes, but the risk of diabetes was greatest with Seroquel.

Seroquel is known generically as (quetiapine fumarate) and it is an oral medication used to manage the symptoms of schizophrenia including: delusions, thought disorder, hallucinations, social withdrawal, lack of energy, apathy, and reduced ability to express emotion.  Seroquel affects a broad range of neurotransmitter receptors, including serotonin receptors.

Seroquel was approved by the FDA for marketing in 1997.  Seroquel is an atypical antipsychotic agent in chemical class called dibenzothiazepine derivatives.

If you or a loved one took Seroquel and suffered side effects, please fill out the form at the right for a free lawsuit case evaluation by a qualified drug side effects attorney.

 

The study of 19,871 U.S. Military Veterans between October 1998 and October 2001 indicated that Seroquel and other members of anti-psychotic drugs posed a higher risk of diabetes.  The effect was most pronounced with Seroquel.

 

Now if the U.S military Veterans studied were all Nam vets then this issue is null and void as far as I am concerned.  Again, unless the study did exclusion testing, which seems the medical profession does not want to admit to toxic chemical damages such as diabetes; then the data is skewed.  Not only ADA diabetes but also a more severe from of “insulin resistance” with or without meeting ADA diabetes testing results. 

 

With that said if a Veteran has diabetes or any sign of diabetes, this medication probably should not be used; only exacerbating an already developing condition.  In my case, my wife found the sugar increase issues and I did not take the VA drugs since no one warned me that I should not take this medication with a diabetic condition.        

 

Seroquel affects a broad range of neurotransmitter receptors, including serotonin and dopamine receptors.

 

Unfortunately for Nam Vets, it seems that the dioxin TCDD caused immune system issues in IL-04 also interferes with dendrites, which are the nerve end receptors.  Therefore, effective nerve communication is compromised.

 


 

A new study at the VA Connecticut Healthcare System, New Haven, Connecticut found that those taking atypical antipsychotic drugs might be at risk for developing high blood sugar (hyperglycemia).

The research, which was conducted by a team led by Dr. Michael J. Sernyak, monitored the frequency of undiagnosed high blood sugar in 647 patients taking various atypical antipsychotics, including: Clozaril (clozapine), Risperdal (risperidone), Zyprexa (olanzapine), Seroquel (quetiapine), or Geodon (ziprasadone).  Over the course of two years, 153 of the participants had a fasting blood sugar result.

The study’s findings, published in the Journal of Clinical Psychiatry for December 2005, show that blood sugar levels were normal for 70% of the subjects, raised in 25% and extremely elevated in just over 5% of the participants. 

Race, ethnicity, age, body mass index (BMI), or psychiatric diagnosis did not appear to have an impact on the development of high blood sugar.

Of all the antipsychotic medications, Clozaril was found to raise blood sugar in significantly more individuals than any of the other medications.  The researchers did not find substantial differences for any of the other drugs.

According to the study, almost one in three patients taking atypical antipsychotics who thought their blood sugar levels were normal actually had abnormalities.  The authors believe this finding should prompt the implementation of periodic screening even in large outpatient populations.

On June 10, newsinfern.com  reported that Eli Lilly had agreed to pay $690 million to settle some 8,000 claims regarding its failure to adequately warn patients that Zyprexa posed an increased risk of diabetes and hyperglycemia.

Specifically, the claims were based on allegations that prior to September 2003, Lilly failed to adequately warn those taking Zyprexa of an increased risk of developing diabetes, hyperglycemia, and related illnesses.

While the pharmaceutical giant did not admit its best-selling drug caused the injuries in question, its potential exposure in the litigation far exceeded the settlement figure.  Thus, as a business decision, resolving about 75% of the claims six months before trial made sense. 

At the time, Jerrold S. Parker, senior partner in the prominent New York personal injury law firm of Parker & Waichman, told reporters that: “It’s really remarkable to arrive at a settlement of this magnitude so far in advance of trial.”

Mr. Parker said that the plaintiffs’ litigation team, made up of some of the foremost products liability attorneys, “was able to convince Lilly that plaintiffs’ case was a strong one, with a good likelihood of success, if it proceeded to trial.                                 
 
The fund will be administered by a panel named by the plaintiffs’ attorneys, which will allocate compensation to the plaintiffs based mostly on the extent of their injuries, which range from weight gain to death.

Zyprexa, like two other powerful antipsychotic drugs, Risperdal (Jannsen Pharmaceuticals) and Seroquel (Astra Zeneca), has been found to cause serious side effects in patients, especially those who have already been diagnosed with diabetes and related illnesses. 

Knowledge of the dangers of Zyprexa was discovered as a result of a series of findings beginning in 2001 when the FDA was alerted to 19 case reports of diabetes associated with the drug. 

One of these cases resulted in death due to necrotizing pancreatitis, a condition in which cells in the pancreas die.  In May 2003, forty additional reports of hyperglycemia (elevated blood sugar), diabetes mellitus, or exacerbation of diabetes were received in the UK including one, which proved to be fatal.

An emergency report issued by the Japanese Health and Welfare Ministry in April of 2002 concerning the side effects of Zyprexa noted that there had been two deaths of patients who had diabetes prior to taking the anti-psychotic medication.  It also reported that there had been seven other patients who lost consciousness or slipped into comas after taking the drug. 

In April of 2003, the Wall Street Journal ran a front-page article on Zyprexa and other anti-psychotics and their link to the development of diabetes.  The article estimated that somewhere around 11 million people have taken Zyprexa. 

An eight-year study found that nearly 300 patients developed diabetes, 75 became seriously ill, and 23 died.  Although the FDA was aware of these cases, it did not require Lilly (and the manufactures of similar antipsychotic drugs) to add a significant warning regarding these risks until September 2003.

Zyprexa has been prescribed to more than 17 million people worldwide since it was first marketed in 1996.  It became Lilly’s best selling medication, after Prozac lost U.S. patent protection in 2001, with annual sales of $4.4 billion or almost 33% of Lilly’s total sales of $13.86 billion.

The results of the newest study serve to confirm the findings reached in previous research as well as the validity of the claims that prompted Lilly’s settlement in June.

 


 

It seems that most of these Anti-psychotic drugs have side effects from serious > to nuisance side effects. 

 

Just be careful!!!!!!!!! 

 

 

Best to all,

Kelley

SP5Kelley2nd94th@aol.com